Material Safety Data Sheet

SECTION 1 - PRODUCT & COMPANY INFORMATION
01	Product Name:	N-Ethylacetamide
02	Synonyms:	C4-H9-N-O, C4-H9-N-O, CH3CONC2H5, acetamide, N-ethyl-, acetamide, N-ethyl-, acetamidoethane, ethylacetamide
03	Chemical Formula:	C4H9NO
04	Molecular Wt:	87.120
05	Company:	RONAK CHEMICALS
06	Address:	4709/1, GIDC Estate, Nr. Sun Pharma Inds. Ltd., Ankleshwar – 393 002, Gujarat, INDIA.

SECTION 2 - Composition/Information on Ingredients
HAZARD RATINGS
NAME	CAS RN	%
N-ethylacetamide	625-50-3	>98

SECTION 3 - Hazards Identification
CANADIAN WHMIS SYMBOLS None EMERGENCY OVERVIEW RISK POTENTIAL HEALTH EFFECTS ACUTE HEALTH EFFECTS
SWALLOWED:	Although ingestion is not thought to produce harmful effects, the material may still be damaging to the health of the individual following ingestion, especially where pre-existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill- health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, ingestion of insignificant quantities is not thought to be cause for concern.
EYE:	Although the liquid is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).
SKIN:	The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. The liquid may be miscible with fats or oils and may degrease the skin, producing a skin reaction described as non-allergic contact dermatitis. The material is unlikely to produce an irritant dermatitis as described in EC Directives . Open cuts, abraded or irritated skin should not be exposed to this material. Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.
INHALED :	The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting. Inhalation hazard is increased at higher temperatures.
CHRONIC HEALTH EFFECTS

SECTION 4 - FIRST AID MEASURES
SWALLOWED:	Immediately give a glass of water. First aid is not generally required. If in doubt, contact a Poisons Information Center or a doctor.
EYE:	If this product comes in contact with eyes:Wash out immediately with water.If irritation continues, seek medical attention.Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.
SKIN:	If skin or hair contact occurs:Flush skin and hair with running water (and soap if available).Seek medical attention in event of irritation.
INHALED :	If fumes or combustion products are inhaled remove from contaminated area.Other measures are usually unnecessary.
NOTES TO PHYSICIAN :	Treat symptomatically..

SECTION 5 - FIRE FIGHTING MEASURES
Vapour Pressure (mmHG):	Not available
Upper Explosive Limit (%):	Not available
Specific Gravity (water=1):	0.924
Lower Explosive Limit (%):	Not available
EXTINGUISHING MEDIA:	Foam.Dry chemical powder.BCF (where regulations permit).Carbon dioxide.Water spray or fog - Large fires only.
FIRE FIGHTING:	Alert Emergency Responders and tell them location and nature of hazard.Wear full body protective clothing with breathing apparatus.Prevent, by any means available, spillage from entering drains or water course.Use water delivered as a fine spray to control fire and cool adjacent area.Avoid spraying water onto liquid pools.Do not approach containers suspected to be hot.Cool fire exposed containers with water spray from a protected location.If safe to do so, remove containers from path of fire.
GENERAL FIRE HAZARDS/HAZARDOUS COMBUSTIBLE PRODUCTS:	Combustible.Slight fire hazard when exposed to heat or flame.Heating may cause expansion or decomposition leading to violent rupture of containers.On combustion, may emit toxic fumes of carbon monoxide (CO).May emit acrid smoke.Mists containing combustible materials may be explosive.Combustion products include: carbon dioxide (CO2), nitrogen oxides (NOx), other pyrolysis products typical of burning organicmaterial.
FIRE INCOMPATIBILITY:	Avoid contamination with oxidizing agents i.e. nitrates, oxidizing acids,chlorine bleaches, pool chlorine etc. as ignition mayresult.
PERSONAL PROTECTION:	Glasses:Chemical goggles.Gloves:Respirator:Type A Filter of sufficient capacity

SECTION 6 - ACCIDENTAL RELEASE MEASURES
MINOR SPILLS :	Remove all ignition sources.Clean up all spills immediately.Avoid breathing vapors and contact with skin and eyes.Control personal contact by using protective equipment.Contain and absorb spill with sand, earth, inert material or vermiculite.Wipe up.Place in a suitable labeled container for waste disposal.
MAJOR SPILLS:	Moderate hazard.Clear area of personnel and move upwind.Alert Emergency Responders and tell them location and nature of hazard.Wear breathing apparatus plus protective gloves.Prevent, by any means available, spillage from entering drains or water course.No smoking, naked lights or ignition sources. Increase ventilation.Stop leak if safe to do so.Contain spill with sand, earth or vermiculite.Collect recoverable product into labeled containers for recycling.Absorb remaining product with sand, earth or vermiculite.Collect solid residues and seal in labeled drums for disposal.Wash area and prevent runoff into drains.If contamination of drains or waterways occurs, advise emergency services.
ACUTE EXPOSURE GUIDELINE LEVELS (AEGL) (in ppm)
AEGL 1:	The airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience notable discomfort, irritation, or certain asymptomatic nonsensory effects. However, the effects are not disabling and are transient and reversible upon cessation of exposure.
AEGL 2:	The airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience irreversible or other serious, long-lasting adverse health effects or an impaired ability to escape.
AEGL 3:	The airborne concentration of a substance above which it is predicted that the general population, including susceptible individuals, could experience life-threatening health effects or death.

SECTION 7 - HANDLING and STORAGE
PROCEDURE FOR HANDLING:	Avoid all personal contact, including inhalation. Wear protective clothing when risk of exposure occurs. Use in a well-ventilated area. Prevent concentration in hollows and sumps. DO NOT enter confined spaces until atmosphere has been checked. Avoid smoking, naked lights or ignition sources. Avoid contact with incompatible materials. When handling, DO NOT eat, drink or smoke.Keep containers securely sealed when not in use. Avoid physical damage to containers. Always wash hands with soap and water after handling. Work clothes should be laundered separately. Use good occupational work practice. Observe manufacturer's storing and handling recommendations. Atmosphere should be regularly checked against established exposure standards to ensure safe working conditions.
RECOMMENDED STORAGE METHODS:	Metal can or drum Packing as recommended by manufacturer. Check all containers are clearly labeled and free from leaks.
STORAGE REQUIREMENTS:	Store in original containers. Keep containers securely sealed. No smoking, naked lights or ignition sources. Store in a cool, dry, well-ventilated area. Store away from incompatible materials and foodstuff containers. Protect containers against physical damage and check regularly for leaks. Observe manufacturer's storing and handling recommendations.
SAFE STORAGE WITH OTHER CLASSIFIED CHEMICALS X: Must not be stored together O: May be stored together with specific preventions +: May be stored together

SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
MATERIAL DATA:	N-ETHYLACETAMIDE: No exposure limits set by NOHSC or ACGIH.
General Hygiene Measures:	Wash thoroughly after handling.
PERSONAL PROTECTION:	Consult your EHS staff for recommendations.
EYE:	Safety glasses with side shields Chemical goggles. Contact lenses pose a special hazard; soft lenses may absorb irritants and all lenses concentrate them.
HANDS/FEET:	Wear general protective gloves, e.g.. light weight rubber gloves. Suitability and durability of glove type is dependent on usage. Important factors in the selection of gloves include: such as: frequency and duration of contact, chemical resistance of glove material, glove thickness and dexterity Select gloves tested to a relevant standard (e.g. Europe EN 374, US F739). When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or higher (breakthrough time greater than 240 minutes according to EN 374) is recommended. When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374) is recommended. Contaminated gloves should be replaced. Gloves must only be worn on clean hands. After using gloves, hands should be washed and dried thoroughly. Application of anon-perfumed moisturiser is recommended. Neoprene gloves
OTHER:	No special equipment needed when handling small quantities. OTHERWISE: Overalls. Barrier cream. Eyewash unit.
RESPIRATOR:	Selection of the Class and Type of respirator will depend upon the level of breathing zone contaminant and the chemical nature of the contaminant. Protection Factors (defined as the ratio of contaminant outside and inside the mask) may also be important. Breathing Zone Level ppm(volume) Maximum Protection Factor Half-face Respirator Full-Face Respirator 1000 10 A-1 - 1000 50 - A-1 5000 50 Airline* - 5000 100 - A-2 10000 100 - A-3 - 100+ - Airline* * * - Continuous Flow ** - Continuous-flow or positive pressure demand. The local concentration of material, quantity and conditions of use determine the type of personal protective equipment required. Use appropriate NIOSH-certified respirator based on informed professional judgement. In conditions where no reasonable estimate of exposure can be made, assume the exposure is in a concentration IDLH and use NIOSH-certified full face pressure demand SCBA with a minimum service life of 30 minutes, or a combination full facepiece pressure demand SAR with auxiliary self-contained air supply. Respirators provided only for escape from IDLH atmospheres shall be NIOSH-certified for escape from the atmosphere in which they will be used.
ENGINEERING CONTROLS:	General exhaust is adequate under normal operating conditions. If risk of overexposure exists, wear an approved respirator. Correct fit is essential to obtain adequate protection. Provide adequate ventilation in warehouse or closed storage areas. Air contaminants generated in the workplace possess varying "escape" velocities which, in turn, determine the "capture velocities" of fresh circulating air required to effectively remove the contaminant. Type of Contaminant: Air Speed: solvent, vapors, degreasing etc., evaporating from tank (in still air) 0.25-0.5 m/s (50-100 f/min) aerosols, fumes from pouring operations, intermittent container filling, low speed conveyer transfers, welding, spray drift, plating acid fumes, pickling (released at low velocity into zone of active generation) 0.5-1 m/s (100-200 f/min.) direct spray, spray painting in shallow booths, drum filling, conveyer loading, crusher dusts, gas discharge (active generation into zone of rapid air motion) 1-2.5 m/s (200-500 f/min) grinding, abrasive blasting, tumbling, high speed wheel generated dusts (released at high initial velocity into zone of very high rapid air motion). 2.5-10 m/s (500-2000 f/min.) Within each range the appropriate value depends on: Lower end of the range Upper end of the range 1: Room air currents minimal or favorable to capture 1: Disturbing room air currents 2: Contaminants of low toxicity or of nuisance value only 2: Contaminants of high toxicity 3: Intermittent, low production. 3: High production, heavy use 4: Large hood or large air mass in motion 4: Small hood - local control only Simple theory shows that air velocity falls rapidly with distance away from the opening of a simple extraction pipe. Velocity generally decreases with the square of distance from the extraction point (in simple cases). Therefore the air speed at the extraction point should be adjusted, accordingly, after reference to distance from the contaminating source. The air velocity at the extraction fan, for example, should be a minimum of 1-2 m/s (200-400 f/min.) for extraction of solvents generated in a tank 2 meters distant from the extraction point. Other mechanical considerations, producing performance deficits within the extraction apparatus, make it essential that theoretical air velocities are multiplied by factors of 10 or more when extraction systems are installed or used.

SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL PROPERTIES Liquid.Does not mix with water.Floats on water.
State:	Liquid	Molecular Weight	87.12
Melting Range (°F):	Not available	Viscosity	Not available
Boiling Range (°F):	194- 197.6 (8 mm Hg)	Solubility in water (g/L)	Partly miscible
Flash Point (°F):	224.006	pH (1% solution)	Not applicable.
Decomposition Temp (°F):	Not available	pH (as supplied)	Not applicable.
Autoignition Temp (°F):	Not available	Vapour Pressure (mmHG)	Not available
Upper Explosive Limit (%):	Not available	Specific Gravity (water=1)	0.924
Lower Explosive Limit (%):	Not available	Relative Vapor Density (air=1)	>1
Volatile Component (%vol):	Not available	Evaporation Rate	Not available
APPEARANCE Light-yellow liquid; does not mix well with water.

SECTION 10 - CHEMICAL STABILITY
CONDITIONS CONTRIBUTING TO INSTABILITY:	Presence of incompatible materials. Product is considered stable. Hazardous polymerization will not occur.
STORAGE INCOMPATIBILITY:	Avoid contamination of water, foodstuffs, feed or seed. Avoid reaction with oxidizing agents.

SECTION 11 - Toxicological Information
TOXICITY AND IRRITATION
unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances.
TOXICITY	IRRITATION
Intraperitoneal (rat) LD50: 3130 mg/kg	Nil Reported
Intraperitoneal (mouse) LD50: 3560 mg/kg

SECTION 12 - ECOLOGICAL INFORMATION
Ecotoxicity
Ingredient	Persistence: Water/Soi	Bioaccumulation	Mobility
N-ethylacetamide	LOW	LOW	HIGH

SECTION 13 - DISPOSAL CONSIDERATIONS

Disposal Instructions All waste must be handled in accordance with local, state and federal regulations. ¦ Legislation addressing waste disposal requirements may differ by country, state and/ or territory. Each user must refer to laws operating in their area. In some areas, certain wastes must be tracked. A Hierarchy of Controls seems to be common - the user should investigate: - Reduction, - Reuse - Recycling - Disposal (if all else fails) This material may be recycled if unused, or if it has not been contaminated so as to make it unsuitable for its intended use. If it has been contaminated, it may be possible to reclaim the product by filtration, distillation or some other means. Shelf life considerations should also be applied in making decisions of this type. Note that properties of a material may change in use, and recycling or reuse may not always be appropriate. DO NOT allow wash water from cleaning equipment to enter drains. Collect all wash water for treatment before disposal. - Recycle wherever possible or consult manufacturer for recycling options. - Consult Waste Management Authority for disposal. - Bury or incinerate residue at an approved site. - Recycle containers if possible, or dispose of in an authorized landfill.

SECTION 14 - Transport Information
NOT REGULATED FOR TRANSPORT OF DANGEROUS GOODS: DOT, IATA, IMDG

SECTION 15 - REGULATORY INFORMATION
N-ethylacetamide (CAS: 625-50-3) is found on the following regulatory lists; "Canada Non-Domestic Substances List (NDSL)","US Toxic Substances Control Act (TSCA) - Inventory"

SECTION 16 - Other Information

Reasonable care has been taken in the preparation of this information, but the author makes no warranty of merchantability or any other warranty, expressed or implied, with respect to this information. The author makes no representations and assumes no liability for any direct, incidental or consequential damages resulting from its use. For additional technical information please call our toxicology department on +800 CHEMCALL. Classification of the mixture and its individual components has drawn on official and authoritative sources as well as independent review by the Chemwatch Classification committee using available literature references. A list of reference resources used to assist the committee may be found at: www.chemwatch.net/references. The (M)SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are Risks in the workplace or other settings. Risks may be determined by reference to Exposures Scenarios. Scale of use, frequency of use and current or available engineering controls must be considered. This document is copyright. Apart from any fair dealing for the purposes of private study, research, review or criticism, as permitted under the Copyright Act, no part may be reproduced by any process without written permission from CHEMWATCH. TEL (+61 3) 9572 4700. Issue Date: Jan-24-2010 Print Date:Apr-21-2010